SEARCHED TERM

Probable tuberculous meningitis (TBM)

DEFINITION

Diagnosed when: 1) a patient presented with clinical features of meningitis and 2) suggestive cerebrospinal fluid laboratory findings of TBM, plus 3) one or more of the following i) chest radiograph findings consistent with pulmonary TB, ii) an extra-meningeal specimen positive for AFB, iii) other evidence of extra-meningeal TB (e.g. abdominal ultrasound features) or iv) brain computed tomography (CT) evidence of TBM.

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SOURCE DEFINITION

Total score of ≥12 when neuroimaging available or total score of ≥10 when neuroimaging unavailable. At least 2 points should either come from CSF or cerebral imaging criteria.

From: Scientific article (PLoS One. )
Year: 2017

OTHER DEFINITIONS

TERM 1

Diagnosed when: 1) a patient presented with clinical features of meningitis and 2) suggestive CSF findings of TBM (total white cell count .5 cells6106/L, protein .0.45 g/L and glucose 2.2 mmol/L), plus 3) one or more of the following i) chest radiograph findings consistent with pulmonary TB, ii) an extra-meningeal specimen positive for AFB, iii) other evidence of extra-meningeal TB (e.g. abdominal ultrasound features) or iv) brain computed tomography (CT) evidence of TBM including one or more of the following: basal meningeal enhancement, hydrocephalus or infarctions.

From: Scientific article (PLoS One. )
Year: 2011

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