SEARCHED TERM
Unconfirmed tuberculosis (for intrathoracic tuberculosis in children)
DEFINITION
Pediatric tuberculosis in which bacteriological confirmation is not obtained and at least 2 of the following conditions are present: Symptoms/signs suggestive of tuberculosis (as defined); Chest radiograph consistent with tuberculosis; Close tuberculosis exposure or immunologic evidence of M. tuberculosis infection; Positive response to tuberculosis treatment (requires documented positive clinical response on tuberculosis treatment—no time duration specified) – With M. tuberculosis infection; Immunological evidence of M. tuberculosis infection(TST and/or IGRA positive) – Without M. tuberculosis infection; No immunological evidence of M. tuberculosis infection. This term was developed for diagnostic research purposes.
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SOURCE DEFINITION
Bacteriological confirmation NOT obtained AND at least 2 of the following: Symptoms/signs suggestive of tuberculosis (as defined); Chest radiograph consistent with tuberculosis; Close tuberculosis exposure or immunologic evidence of M. tuberculosis infection; Positive response to tuberculosis treatment (requires documented positive clinical response on tuberculosis treatment—no time duration specified) - With M. tuberculosis infection; Immunological evidence of M.tuberculosis infection(TSTand/orIGRA positive) - Without M. tuberculosis infection; No immunological evidence of M. tuberculosis infection.
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