SEARCHED TERM
Drug-susceptible tuberculosis
DEFINITION
Disease caused by a strain of M. tuberculosis that is susceptible to the most commonly used anti-tuberculosis drugs (isoniazid, rifampicin, pyrazinamide, and ethambutol).
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SOURCE DEFINITION
Bacteria are said to be sensitive to a drug when the drugs are effective in killing or stopping the multiplication of bacteria in the body and can therefore clear the infection. The strains of TB which are sensitive to all first-line drugs are called drug-susceptible.
OTHER DEFINITIONS
TB caused by bacilli that are killed by anti-TB medicines
Patients with no evidence of infection with strains resistant to rifampicin (i.e. not rifampicin-resistant or multidrug-resistant TB)
A bacteriologically confirmed or clinically diagnosed case of TB without evidence of infection with strains resistant to rifampicin and isoniazid.
A bacteriologically confirmed or clinically diagnosed case of TB, without evidence of infection with strains resistant to isoniazid and rifampicin.
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