SEARCHED TERM
Primary drug resistance
DEFINITION
Presence of drug resistance to one or more anti-tuberculosis drugs in a person who has received either no or less than one month of prior tuberculosis chemotherapy.
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SOURCE DEFINITION
Primary resistance occurs in persons who have never been treated for TB and who were presumably infected with a resistant strain of M. tuberculosis.
OTHER DEFINITIONS
The presence of drug resistance to one or more anti-TB drugs in a TB patient who has received either no or less than one month of prior TB chemotherapy
Proxy to Drug resistance among new cases
Patients infected with M. tuberculosis that is resistant to anti-TB drugs from the outset, prior to anti-TB treatment
Patients who are diagnosed with TB and who harbour organisms resistant to one or more anti-TB drugs, but have never been previously treated for TB or have been treated for less than one month
DR-TB that results from transmission of a DR M tuberculosis strain. This could be any of the after clinical situation in a child newly diagnosed with confirmed or probable DR-TB: (a) never treated: a child with out previous TB treatment who has not yet received any TB treatment; or (b) previously treated: a child who was previously treated with first-line drugs who was either cured or completed that treatment regimen; or (c) currently receiving treatment: a child who is receiving first-line drugs for presumed drug susceptible TB disease
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