Change from sputum smear-positive to sputum smear negative or from culture-positive to culture-negative. Culture conversion is the most useful indicator that treatment for RR/MDR-TB has been effective

Two consecutive negative smears and cultures taken 30 days apart

Changing from sputum smear-positive to sputum smear negative. Sputum conversion is the best indicator that initial phase TB treatment has been effective

Change in the result of a test for M. tuberculosis infection that is interpreted to indicate a change from being uninfected to infected. With the tuberculin skin test, an increase of >10 mm in induration size during <2 years is defined as a conversion. A conversion is presumptive evidence of new M. tuberculosis infection and poses an increased risk for progression to TB disease. The term is applied to contacts only when previous skin test results are available. A change in tuberculin status during the window period is not necessarily consistent with this definition.

Change from sputum smear-positive to sputum smear negative or from culture-positive to culture-negative. Culture conversion is the most useful indicator that treatment for RR/MDR-TB has been effective

Two consecutive negative smears and cultures taken 30 days apart

Changing from sputum smear-positive to sputum smear negative. Sputum conversion is the best indicator that initial phase TB treatment has been effective