Drug resistance
Line-probe assay (LPA)
Rapid technique based on polymerase chain reaction (PCR) that is used to detect the most common mutations of M. tuberculosis that confer resistance to anti-tuberculosis drugs. It is also used to detect the species of multiple nontuberculous mycobacteria.
Injectable agent
In the tuberculosis context, it refers to aminoglucosides such as amikacin, capreomycin, kanamycin, or streptomycin, previously considered to be key MDR-TB regimen components (the term as used here does not include the second-line TB drugs imipenem and meropenem that are also given by injection).
Drug-resistant tuberculosis (DR-TB) management centre
Specialized public or private health facility that provides comprehensive management for persons with DR-TB including diagnosis, treatment initiation, and monitoring.
Confirmed case of multi-drug resistant tuberculosis (MDR-TB)
Person with a positive culture for M. tuberculosis which has been confirmed through a drug-susceptibility test to be resistant in vitro to at least isoniazid and rifampicin.
