Any person who has been exposed to a person with tuberculosis.

Contact investigation

Systematic screening of people with previously undiagnosed tuberculosis or M. tuberculosis infection among the contacts of an index case of tuberculosis in the household and in comparable settings in which transmission occurs. It consists of identification, screening, clinical evaluation and/or testing, as appropriate.

Active case-finding

Proactive strategy used to find tuberculosis cases in health facilities or in the community. It usually implies a systematic screening process in high-risk populations.

WHO four-symptom screen

The presence of either cough, fever, weight loss, or night sweats used as a screening test in people living with HIV.

Tuberculin skin test (TST) conversion rate

Proportion of a population in which TST results converted within a specified time. It is calculated by dividing the number of TST conversions among persons in the setting in a specified period (numerator) by the number of persons who received TSTs in the setting over the same period (denominator), multiplied by 100. It is not a true rate.

Provider-initiated tuberculosis screening pathway

The provider-initiated tuberculosis screening pathway systematically targets people at high risk of exposure or of developing tuberculosis and screens them by assessing symptoms, using tests, examinations, or other procedures to identify those who might have tuberculosis, following up with a diagnostic test and additional clinical assessments to make a definite diagnosis.

Persistent cough

Cough with a duration of >2 weeks. Also referred to as prolonged or unremitting cough.

Persistent unexplained fever

Persistent (>1 week) and unexplained fever (> 38.0C) reported by a guardian or objectively recorded at least once.

Epidemiologic (epi) link

Characteristic that two people with tuberculosis share that explains where and when tuberculosis could have been transmitted between them.


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