Tuberculosis preventive treatment (TPT)

Treatment offered to people considered at risk of tuberculosis to reduce that risk. Also referred to as “treatment of M. tuberculosis infection” or “tuberculosis preventive therapy”.

Treatment support

An approach to supporting patients who are taking prescribed doses of anti-tuberculosis drugs, to help ensure adherence to treatment and maximize its efficacy.

Treatment supporter

Trained health worker or trained and supervised community member who directly observes a TB or DR-TB patient’s treatment. When it is not convenient for a person with tuberculosis to visit a health facility during regular hours, a community-based treatment supporter may be selected to directly observe the person’s treatment at a more convenient place and time or through the use of novel technologies (video-DOT), which might not observe TB treatment in real time.

Treatment completed (treatment outcome)

A person who completed anti-tuberculosis treatment as recommended by the national policy, whose outcome does not meet the definition for cure or treatment failure.

Standardized treatment

In the tuberculosis context, it is a treatment regimen that is the same for all patients with similar characteristics or a similar type of tuberculosis. This is the opposite of individualized treatment.

Second-line drug

Agent usually reserved for the treatment of drug-resistant tuberculosis. First-line tuberculosis drugs used to treat drug-susceptible tuberculosis – ethambutol, isoniazid and pyrazinamide – may also be used in MDR-TB regimens.


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