Adherence-enhancing strategy in which a trained health-care professional or other specially trained person watches a patient swallow each dose of medication and records the dates that the medication was taken. DOT is the standard of care for all patients with TB disease and should be used for all doses during the course of treatment for TB disease and for LTBI whenever feasible. All patients on intermittent (i.e., once- or twice-weekly) treatment for TB disease or LTBI should receive DOT. Plans for DOT should be coordinated with the state or local health department. Rates of relapse and development of drugresistance are decreased when DOT is used

Adherence-enhancing strategy in which a health-care worker or other trained person watches a patient swallow each dose of medication and is accountable to the public health system. DOT is the preferred method of care for all patients with TB disease and is a preferred option for patients under treatment for latent infection

Adherence-enhancing strategy in which an HCW or other trained person watches a patient swallow each dose of medication. DOT is the standard care for all patients with TB disease and is a preferred option for patients treated for LTBI

Treatment observed by a health worker or a community TB treatment supporter. The health worker or community TB treatment supporter actually watches the TB patient swallow the drugs at every time that a dose is schedule

Trained and supervised person observes the patient swallowing the tablets

Administration of each dose of medication, such as swallowing TB tablets, observed by health staff or another designated, trained and monitored individual in the community